Empirical antibiotic therapy for febrile neutropenia in paediatric oncology patients
نویسندگان
چکیده
منابع مشابه
The role of mannose-binding lectin (MBL) in paediatric oncology patients with febrile neutropenia.
Children with cancer often have fever during chemotherapy-induced neutropenia, but only some develop serious infectious complications. Mannose-binding lectin (MBL) deficiency might increase infection susceptibility in these children. MBL genotype and phenotype were prospectively determined in 110 paediatric oncology patients. During febrile neutropenia, MBL concentrations were measured longitud...
متن کاملConsensus on diagnosis and empiric antibiotic therapy of febrile neutropenia
Controversial issues on the management of empiric therapy and diagnosis of febrile neutropenia (FN) were faced by a Consensus Group of the Italian Association of Pediatric Hematology-Oncology (AIEOP). In this paper we report the suggestions of the consensus process regarding the role of aminoglycosides, glycopeptides and oral antibiotics in empiric therapy of FN, the rules for changing or disco...
متن کاملEarly discontinuation of intravenous antimicrobial therapy in pediatric oncology patients with febrile neutropenia
BACKGROUND There are no standard criteria for when to discontinue intravenous antimicrobial therapy (IVAMT) in children with febrile neutropenia (FN), but it is now common to discontinue IVAMT and discharge patients with an absolute neutrophil count (ANC) < or = 500/mm3. The purpose of this study was to evaluate the outcome of a large cohort of children with FN who had IVAMT discontinued with a...
متن کاملEarly Empiric Antibiotic Therapy for Febrile Neutropenia Patients at Low Risk.
Although it is apparent that certain patients with febrile neutropenic episodes can benefit from outpatient antibiotic therapy, not all low-risk patients are treated in this fashion. There are barriers, real and perceived, to implementing this approach for patients, health care providers, and caregivers. Table 3 summarizes the advantages and disadvantages of ambulatory management of febrile neu...
متن کاملOutpatient versus inpatient IV antibiotic management for pediatric oncology patients with low risk febrile neutropenia: a randomised trial.
BACKGROUND Febrile neutropenia (FN) is a frequent, serious complication of intensive pediatric chemotherapy regimens. The aim of this trial was to compare quality of life (QOL) between inpatient and outpatient intravenous antibiotic management of children and adolescents with low risk febrile neutropenia (LRFN). PROCEDURE In this randomised non-blinded trial, patients between 1 and 21 years o...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2019
ISSN: 1465-1858
DOI: 10.1002/14651858.cd009653.pub2